{"id":1000586,"date":"2026-05-09T10:46:24","date_gmt":"2026-05-09T10:46:24","guid":{"rendered":"https:\/\/bodyflexpeptides.com\/?post_type=product&p=1000586"},"modified":"2026-05-09T12:33:56","modified_gmt":"2026-05-09T12:33:56","slug":"pnc-27","status":"publish","type":"product","link":"https:\/\/bodyflexpeptides.com\/?product=pnc-27","title":{"rendered":"PNC-27"},"content":{"rendered":"

Overview<\/h3>\n

PNC-27 is a 32\u2013amino acid chimeric peptide composed of two functional regions: residues 12\u201326 of the p53 transactivation domain, which contains the HDM-2 binding motif, fused to a membrane-residency penetratin-like sequence at the C-terminus.<\/p>\n

Research Background<\/h3>\n

PNC-27 has been studied in oncology research focused on selective targeting of cancer cells. Published studies report its activity on a range of solid-tumor lines and certain leukemia models that express HDM-2 in their plasma membrane.<\/p>\n

Storage & Handling<\/h3>\n

Store lyophilized peptide at -20\u00b0C for long-term stability. Once reconstituted with bacteriostatic water, store at 2\u20138\u00b0C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.<\/p>\n

Disclaimer:<\/strong>
\nThis product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.<\/p>\n","protected":false},"excerpt":{"rendered":"

CAS Number:<\/strong> 1159861-00-3<\/p>\n

Overview:<\/strong>
\nPNC-27 is a chimeric anticancer research peptide combining a p53-derived HDM-2-binding domain with a membrane-penetrating sequence, studied for its selective lysis of cancer cells expressing membrane HDM-2.<\/p>\n","protected":false},"featured_media":1000671,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[124,126],"product_tag":[],"class_list":["post-1000586","product","type-product","status-publish","has-post-thumbnail","product_cat-all-peptides","product_cat-single-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=\/wp\/v2\/product\/1000586","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1000586"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=\/wp\/v2\/media\/1000671"}],"wp:attachment":[{"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1000586"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=1000586"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=1000586"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/bodyflexpeptides.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=1000586"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}