Semaglutide

Description

Overview

Semaglutide is a synthetic peptide analog of human glucagon-like peptide-1 (GLP-1) with two key modifications: a fatty acid (C18 diacid) conjugation that enables albumin binding, and an Aib substitution at position 2 that prevents DPP-4 cleavage. Together these changes substantially extend its half-life compared to native GLP-1.

Research Background

Semaglutide has been studied extensively in research on glucose regulation, energy balance, gastric motility, and cardiovascular outcomes. It is one of the most widely characterized GLP-1 receptor agonists in current incretin research.

Storage & Handling

Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.

Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.