SLU-PP-332

Description

Overview

SLU-PP-332 is a synthetic small-molecule compound developed at Saint Louis University as an agonist of the estrogen-related receptor (ERR) family of orphan nuclear receptors. It activates all three ERR isoforms with preferential potency at ERRα (EC50 ≈ 98 nM), classifying it as a pan-ERR agonist.

Research Background

SLU-PP-332 has been studied in research on metabolic regulation, exercise mimetics, cardiac function, and mitochondrial biology. Animal model studies have reported induction of an aerobic exercise gene-expression program, increased exercise endurance, and protective effects in heart-failure models.

Storage & Handling

Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.

Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.