01 / 01Epithalon
Research peptide
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on a fragment of the pineal-derived peptide preparation Epithalamin and studied for its effects on telomerase activity and circadian biology.
For laboratory research use only. Not for human or animal consumption.
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Additional information
- Full name
- Epitalon (Epithalon)
- CAS number
- 307297-39-8
- Molecular formula
- C₁₄H₂₂N₄O₉
- Molecular weight
- 390.35 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
Epithalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly, developed within the Khavinson bioregulator research program at the St. Petersburg Institute of Bioregulation and Gerontology. It is the synthetic analog of Epithalamin, a complex pineal extract.
Research Background
Epithalon has been studied for its reported effects on telomerase activity, circadian melatonin rhythms, and age-related changes in cellular function. Research has spanned cell culture, rodent models, and small clinical-style observational studies in aging populations.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
Epithalon is reported to upregulate the catalytic subunit of telomerase (TERT), increasing telomerase activity and elongating telomeres in cultured somatic cells in published in vitro studies. It is also studied for modulation of pineal melatonin synthesis, with effects on circadian rhythm gene expression observed in animal models.
03Research applications
Epithalon is studied across research models in telomere biology, cellular aging, circadian regulation, and pineal endocrinology. It is a reference compound in the broader peptide bioregulator literature.
04Technical specifications
05Certificate / documentation
Certificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.



