01 / 01Recovery & Repair
TB-500
2 mg / 5 mg / 10 mg
Research peptide
COA Available Batch Documentation● In Stock
Price Price range: $19.95 through $78.95
TB-500 is a synthetic peptide fragment of Thymosin Beta-4, a protein involved in cellular protection, regeneration, and repair processes. In laboratory studies, TB-500 has been explored for its role in promoting cell migration, angiogenesis, and muscle recovery.
For laboratory research use only. Not for human or animal consumption.
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Additional information
- Full name
- Thymosin Beta-4 (43 aa)
- CAS number
- 77591-33-4
- Molecular formula
- C₂₁₂H₃₅₀N₅₆O₇₈S
- Molecular weight
- 4963.49 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Handling & warranty
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
TB-500 is a synthetic 17–amino acid fragment derived from Thymosin Beta-4 (TB4), a naturally occurring regenerative peptide found in nearly all human and animal cells. The fragment retains the active region of TB4 responsible for actin-binding and cellular regulation activity.
Research Background
TB-500 has been investigated in preclinical models of soft tissue, tendon, ligament, skin, and corneal repair. Research has focused on its role in cell migration, blood vessel formation, and modulation of inflammation through actin-cytoskeleton dynamics.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
TB-500 is built around the actin-binding domain of Thymosin Beta-4 and acts primarily by sequestering G-actin, regulating cytoskeletal organization. This activity supports cell migration, differentiation, and proliferation. Studies have also reported upregulation of vascular endothelial growth factor (VEGF) and modulation of inflammatory cytokines, contributing to angiogenic and regenerative pathways in tissue repair models.
03Research applications
Preclinical research has explored TB-500 in models of muscle, tendon, and ligament injury, dermal wound repair, corneal healing, and cardiac tissue protection. Its low molecular weight and broad tissue distribution make it a frequent reference compound in regenerative peptide studies.
04Technical specifications
CompoundTB-500
Full nameThymosin Beta-4 (43 aa)
Strength2 mg / 5 mg / 10 mg
CAS number77591-33-4
Molecular formulaC₂₁₂H₃₅₀N₅₆O₇₈S
Molecular weight4963.49 g/mol
Research areaRecovery & Repair
FormLyophilized powder
Purity99% HPLC (per label)
DocumentationCOA available
05Certificate / documentation
Certificate of AnalysisLot-specific documentation
AvailableCertificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.
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