01 / 01Cognitive & Neuro
Kisspeptin-10
5 mg / 10 mg
Research peptide
COA Available Batch Documentation● In Stock
Price Price range: $44.95 through $79.95
Kisspeptin is a hypothalamic peptide encoded by the KISS1 gene that acts as a primary regulator of the reproductive endocrine axis through its receptor, KISS1R (GPR54).
For laboratory research use only. Not for human or animal consumption.
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Additional information
- CAS number
- 817204-33-4
- Molecular formula
- C₆₃H₈₃N₁₇O₁₄
- Molecular weight
- 1302.50 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Handling & warranty
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
Kisspeptin is a peptide product of the KISS1 gene, with multiple biologically active fragments (Kisspeptin-54, -14, -13, and -10) sharing a common C-terminal RF-amide sequence. It is the principal upstream activator of GnRH neurons in the hypothalamus.
Research Background
Kisspeptin is central to research on reproductive neuroendocrinology, puberty onset, and HPG (hypothalamic-pituitary-gonadal) axis regulation. It has been studied in models of fertility, hypogonadism, and metabolic-reproductive crosstalk.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
Kisspeptin binds the GPCR KISS1R (GPR54), expressed predominantly on GnRH-secreting neurons. Receptor activation drives Gq-coupled phospholipase C signaling, increasing intracellular calcium and triggering pulsatile GnRH release into the hypophyseal portal system, which in turn stimulates LH and FSH secretion from the anterior pituitary.
03Research applications
Kisspeptin is studied in research on puberty, fertility, reproductive endocrinology, and metabolic regulation of reproduction. It is a foundational reference peptide for investigators examining upstream control of the GnRH pulse generator.
04Technical specifications
CompoundKisspeptin-10
Strength5 mg / 10 mg
CAS number817204-33-4
Molecular formulaC₆₃H₈₃N₁₇O₁₄
Molecular weight1302.50 g/mol
Research areaCognitive & Neuro
FormLyophilized powder
Purity99% HPLC (per label)
DocumentationCOA available
05Certificate / documentation
Certificate of AnalysisLot-specific documentation
AvailableCertificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.
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