01 / 015-Amino-1MQ
10 mg
Research peptide
COA Available Batch Documentation● In Stock
Price$29.95
5-Amino-1MQ is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT) studied in research on adipose tissue, NAD+ biology, and methyl-donor regulation.
For laboratory research use only. Not for human or animal consumption.
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Additional information
- Full name
- 5-Amino-1-methylquinolinium iodide
- CAS number
- 62445-32-5
- Molecular formula
- C₁₀H₁₁IN₂
- Molecular weight
- 286.11 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Handling & warranty
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, orally available selective inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT methylates nicotinamide to 1-methylnicotinamide using S-adenosylmethionine as the methyl donor.
Research Background
5-Amino-1MQ has been studied in research on adipose tissue metabolism, NAD+ biology, and methyl-donor flux. NNMT is overexpressed in adipocytes from obese subjects in published research, making it a target of interest in metabolic studies.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
5-Amino-1MQ selectively inhibits NNMT, an enzyme that methylates nicotinamide and consumes the methyl donor SAM. By blocking this reaction, 5-Amino-1MQ research is reported to increase intracellular nicotinamide (a precursor for NAD+ salvage), preserve SAM and the SAM:SAH ratio (modulating methylation biology), and influence adipocyte energy expenditure pathways including the increase of polyamine-related signaling.
03Research applications
5-Amino-1MQ is studied in research on adipose tissue biology, NAD+ metabolism, methylation pathways, and NNMT-targeted pharmacology. It is a reference compound in NNMT-inhibitor research.
04Technical specifications
Compound5-Amino-1MQ
Full name5-Amino-1-methylquinolinium iodide
Strength10 mg
CAS number62445-32-5
Molecular formulaC₁₀H₁₁IN₂
Molecular weight286.11 g/mol
Research areaMetabolic Research
FormLyophilized powder
Purity99% HPLC (per label)
DocumentationCOA available
05Certificate / documentation
Certificate of AnalysisLot-specific documentation
AvailableCertificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.
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