01 / 01GHRP / GHRH Research
CJC-1295 with DAC
5 mg
Research peptide
COA Available Batch Documentation● In Stock
Price$39.95
CJC-1295 with DAC is a long-acting GHRH analog featuring a Drug Affinity Complex (DAC) maleimide that covalently binds serum albumin, dramatically extending its plasma half-life.
For laboratory research use only. Not for human or animal consumption.
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Additional information
- CAS number
- 863288-34-0
- Molecular formula
- C₁₆₅H₂₆₉N₄₇O₄₆
- Molecular weight
- 3647.19 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Handling & warranty
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
CJC-1295 with DAC is a modified analog of GHRH(1-29) (Sermorelin) with four amino acid substitutions for stability against proteolysis and a maleimidopropionic acid (DAC, Drug Affinity Complex) linker. The DAC group reacts with cysteine 34 of circulating serum albumin to form a covalent bond, extending the peptide’s half-life from minutes to several days.
Research Background
CJC-1295 with DAC has been investigated in research on the somatotropic axis as a tool for studying sustained, rather than pulsatile, GHRH receptor activation. It contrasts with short-acting GHRH analogs such as Sermorelin.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
After albumin binding, CJC-1295 circulates with a half-life of approximately 6–8 days and continuously engages the GHRH receptor on pituitary somatotrophs, activating Gs-coupled cAMP signaling. This produces a prolonged elevation in baseline GH and IGF-1 levels in research models — a pharmacological profile distinct from the brief pulses elicited by native GHRH.
03Research applications
CJC-1295 with DAC is studied in research on the somatotropic axis, sustained GHRH receptor activity, body composition, and IGF-1 biology. It is a reference compound for albumin-tethered peptide pharmacology.
04Technical specifications
CompoundCJC-1295 with DAC
Strength5 mg
CAS number863288-34-0
Molecular formulaC₁₆₅H₂₆₉N₄₇O₄₆
Molecular weight3647.19 g/mol
Research areaGHRP / GHRH Research
FormLyophilized powder
Purity99% HPLC (per label)
DocumentationCOA available
05Certificate / documentation
Certificate of AnalysisLot-specific documentation
AvailableCertificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.
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