01 / 01Cognitive & Neuro
VIP
10 mg
Research peptide
COA Available Batch Documentation● In Stock
Price$44.95
Vasoactive Intestinal Peptide (VIP) is a 28–amino acid neuropeptide of the secretin/glucagon superfamily studied for its broad roles in vasodilation, immune regulation, and circadian biology.
For laboratory research use only. Not for human or animal consumption.
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Additional information
- Full name
- Vasoactive Intestinal Peptide
- CAS number
- 37221-79-7
- Molecular formula
- C₁₄₇H₂₃₈N₄₄O₄₂S
- Molecular weight
- 3325.83 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Handling & warranty
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
VIP is a 28–amino acid peptide originally isolated from porcine intestine by Said and Mutt. It is widely distributed in central and peripheral neurons, enteric ganglia, and immune cells, and belongs to the secretin/glucagon peptide superfamily.
Research Background
VIP has been studied in research on vasodilation, intestinal physiology, immune modulation, circadian regulation, and pulmonary biology. It is a foundational reference peptide for VPAC receptor pharmacology.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
VIP binds two G-protein-coupled receptors, VPAC1 and VPAC2, both Gs-coupled and activating cAMP/PKA signaling. Effects include vascular smooth muscle relaxation, modulation of intestinal water and electrolyte secretion, inhibition of pro-inflammatory cytokines (TNF-α, IL-6) with promotion of regulatory T-cell phenotypes, and influence on suprachiasmatic nucleus circadian signaling.
03Research applications
VIP is studied in research on vasodilation, gastrointestinal physiology, immune modulation, circadian biology, and pulmonary function. It is a reference peptide for VPAC receptor research.
04Technical specifications
CompoundVIP
Full nameVasoactive Intestinal Peptide
Strength10 mg
CAS number37221-79-7
Molecular formulaC₁₄₇H₂₃₈N₄₄O₄₂S
Molecular weight3325.83 g/mol
Research areaCognitive & Neuro
FormLyophilized powder
Purity99% HPLC (per label)
DocumentationCOA available
05Certificate / documentation
Certificate of AnalysisLot-specific documentation
AvailableCertificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.
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