01 / 01GHK-Cu
Research peptide
GHK-Cu is a copper-binding tripeptide (glycyl-L-histidyl-L-lysine) naturally present in human plasma and studied for its role in tissue remodeling, antioxidant signaling, and gene expression modulation.
For laboratory research use only. Not for human or animal consumption.
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Additional information
- Full name
- Copper tripeptide-1 (GHK-Cu)
- CAS number
- 49557-75-7
- Molecular formula
- C₁₄H₂₂CuN₆O₄
- Molecular weight
- 401.91 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
GHK-Cu is the copper(II)-bound complex of the tripeptide glycyl-L-histidyl-L-lysine. It occurs naturally in human plasma at levels that decline with age and has been characterized as a multi-functional signaling peptide.
Research Background
GHK-Cu is widely investigated in dermal research, wound healing models, and gene-expression studies. It has been reported to modulate hundreds of genes involved in extracellular matrix remodeling, antioxidant defense, and regulation of inflammation.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
GHK-Cu binds copper(II) with high affinity and serves as a copper carrier in research systems, modulating activity of copper-dependent enzymes including superoxide dismutase and lysyl oxidase. Gene-expression studies have shown GHK-Cu modulates a broad set of genes involved in collagen and glycosaminoglycan synthesis, fibroblast proliferation, and DNA repair pathways.
03Research applications
GHK-Cu is studied in models of skin biology, wound repair, hair follicle research, and antioxidant signaling. Its broad transcriptional footprint makes it a reference compound for investigators exploring peptide-mediated modulation of gene expression.
04Technical specifications
05Certificate / documentation
Certificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.



