01 / 01GHRP / GHRH Research
Sermorelin
2 mg / 5 mg / 10 mg
Research peptide
COA Available Batch Documentation● In Stock
Price Price range: $14.95 through $64.95
Sermorelin is a synthetic 29–amino acid peptide corresponding to the biologically active fragment of growth hormone-releasing hormone (GHRH 1-29).
For laboratory research use only. Not for human or animal consumption.
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Additional information
- Full name
- Sermorelin (GRF 1-29 amide)
- CAS number
- 86168-78-7
- Molecular formula
- C₁₄₉H₂₄₆N₄₄O₄₂S
- Molecular weight
- 3357.89 g/mol
- Purity
- 99% HPLC
- Form
- Lyophilized powder
Identifiers as printed on the product label. Refer to the lot-specific COA for batch data.
Handling & warranty
Reconstitution Warranty Notice (Research Use Only)
For laboratory research use only. Not for human use.- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution should be performed using the recommended bacteriostatic water and handled according to accepted research practices.
- Any applicable warranty related to reconstitution, sterility or material integrity is subject to the stated handling requirements.
- Use of unsuitable third-party diluents or deviation from provided handling guidance may affect applicable warranty coverage.
01Product details
Overview
Sermorelin is a synthetic analog of the first 29 amino acids of human growth hormone-releasing hormone (GHRH), the shortest fully bioactive fragment of the molecule. It functions as a GHRH receptor agonist on pituitary somatotrophs.
Research Background
Sermorelin is widely used in research as a reference GHRH agonist in studies of pituitary function, growth hormone (GH) pulsatility, and the somatotropic axis. It has been examined in models of age-related GH decline, body composition, sleep architecture, and metabolic regulation.
Storage & Handling
Store lyophilized peptide at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2–8°C and use within recommended timeframes. Handle under sterile laboratory conditions and avoid repeated freeze-thaw cycles.
Disclaimer:
This product is for laboratory research use only. It is not intended for human or animal consumption or for use in any diagnostic, therapeutic, or clinical applications.
02Mechanism of action
Sermorelin binds the growth hormone-releasing hormone receptor (GHRHR) on pituitary somatotrophs, activating Gs-coupled cAMP signaling. This stimulates synthesis and pulsatile release of endogenous growth hormone while preserving the negative-feedback loop with somatostatin and IGF-1, distinguishing it from direct exogenous GH administration.
03Research applications
Sermorelin is studied in research on pituitary function, growth hormone secretion patterns, body composition, and aging biology. It is a frequent comparator for newer GHRH analogs such as CJC-1295 and Tesamorelin.
04Technical specifications
CompoundSermorelin
Full nameSermorelin (GRF 1-29 amide)
Strength2 mg / 5 mg / 10 mg
CAS number86168-78-7
Molecular formulaC₁₄₉H₂₄₆N₄₄O₄₂S
Molecular weight3357.89 g/mol
Research areaGHRP / GHRH Research
FormLyophilized powder
Purity99% HPLC (per label)
DocumentationCOA available
05Certificate / documentation
Certificate of AnalysisLot-specific documentation
AvailableCertificates of Analysis are issued per lot. Request the COA for your lot and our team will send it to you by email.
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